Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 13/20 | 0.55 |
| ▸ | CTSC | P53634 | 6/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20711876 | 1.00 | SSTR4 (0.55) | SSTR4CTSCCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4956052 | 0.85 | SSTR4 (0.52) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL21625333 | 0.84 | SSTR4 (0.51) | SSTR4CTSCKCNH2 | |
| SCHEMBL21902109 | 0.84 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL20715370 | 0.84 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL670479 | 0.84 | SSTR4 (0.55) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL7598637 | 0.83 | SSTR4 (0.50) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL7598015 | 0.81 | SSTR4 (0.48) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL4967939 | 0.79 | SSTR4 (0.48) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL10908504 | 0.78 | SSTR4 (0.53) | SSTR4CTSCSSTR1SSTR2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349969-B | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阵列生物制药公司 | 2022-05-10 | — | — | CN | disclosed |