Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 16/20 | 0.48 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6624381 | 0.89 | SSTR4 (0.47) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL26724416 | 0.86 | SSTR4 (0.47) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL18664463 | 0.83 | SSTR4 (0.52) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL18664465 | 0.83 | SSTR4 (0.52) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL8860932 | 0.83 | SSTR4 (0.52) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL487610 | 0.79 | SSTR4 (0.49) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL6039537 | 0.79 | SSTR4 (0.49) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL29516296 | 0.79 | SSTR4 (0.55) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL20711876 | 0.79 | SSTR4 (0.55) | SSTR4CTSCSSTR1SSTR2SSTR3 | |
| SCHEMBL5634966 | 0.79 | SSTR4 (0.48) | SSTR4CTSCSSTR1SSTR2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959959-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2008-08-27 | — | — | EP | claimed |
| WO-2007067511-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-06-14 | — | — | WO | claimed |
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1959959-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067511-A2 | MORPHOLINE CARBOXAMIDE PROKINETICIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2007-06-14 | — | — | WO | disclosed |