Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.76 |
| ▸ | MAPT | P10636 | 10/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | ALPL | P05186 | 1/20 | 0.76 |
| ▸ | ALPI | P09923 | 1/20 | 0.76 |
| ▸ | ALPG | P10696 | 1/20 | 0.76 |
| ▸ | CRHBP | P24387 | 1/20 | 0.72 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | STK17B | O94768 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28722336 | 1.00 | KMT2A (0.76) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL22624945 | 0.86 | KMT2A (1.00) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4144172 | 0.83 | KMT2A (0.75) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3566759 | 0.81 | ERBB2 (0.59) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL3566755 | 0.81 | ERBB2 (0.59) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL13343867 | 0.81 | ERBB2 (0.59) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18099456 | 0.80 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5477780 | 0.80 | ERBB2 (0.76) | MAPTALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL5477779 | 0.80 | ERBB2 (0.76) | MAPTALDH1A1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL7843430 | 0.80 | ERBB2 (0.76) | MAPTALDH1A1SMN1; SMN2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349743-A | Heterocycle-containing orange ketone derivative and antibacterial application | 中国科学院新疆理化技术研究所 | 2022-04-15 | — | — | CN | disclosed |