Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.53 |
| ▸ | NMT2 | O60551 | 1/20 | 0.44 |
| ▸ | NMT1 | P30419 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517462 | 0.98 | GNPAT (0.54) | GNPATFOLH1NMT2NMT1GRIN2D | |
| SCHEMBL24616813 | 0.94 | GRIN2D (0.49) | GNPATFOLH1NMT2NMT1GRIN2D | |
| SCHEMBL22648216 | 0.94 | GRIN2D (0.49) | GNPATFOLH1NMT2NMT1GRIN2D | |
| SCHEMBL29517235 | 0.93 | GNPAT (0.48) | GNPATFOLH1NMT2NMT1GRIN2D | |
| SCHEMBL24616812 | 0.93 | GRIN2D (0.49) | GNPATFOLH1NMT2NMT1GRIN2D | |
| SCHEMBL29517516 | 0.92 | GNPAT (0.59) | GNPATFOLH1SIRT5TASP1 | |
| SCHEMBL29517310 | 0.92 | GNPAT (0.59) | GNPATFOLH1SIRT5TASP1 | |
| SCHEMBL29517504 | 0.92 | GNPAT (0.59) | GNPATFOLH1SIRT5TASP1 | |
| SCHEMBL29517694 | 0.92 | GNPAT (0.59) | GNPATFOLH1SIRT5TASP1 | |
| SCHEMBL24616820 | 0.91 | GRIN2D (0.49) | GNPATFOLH1NMT2NMT1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966234-A1 | VASCULAR CHOLESTEROL INHIBITORS AND USE THEREOF | Consejo Superior De Investigaciones Científicas (ES) | 2022-03-16 | — | — | EP | disclosed |