SCHEMBL29518017

SCHEMBL29518017

O=C(O)CC[Si](O)(O)O.[Al]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.47
EGLN1 Q9GZT9 3/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
TSHR P16473 4/20 0.45
SLC22A6 Q4U2R8 1/20 0.42
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
HDAC3 O15379 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC8 Q9BY41 2/20 0.38
FFAR3 O14843 1/20 0.38
KMT2A Q03164 2/20 0.36
SLC15A2 Q16348 1/20 0.36
MAPK1 P28482 1/20 0.36
SLC13A3 Q8WWT9 1/20 0.36
OR51E2 Q9H255 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL736970 0.97
SCHEMBL29703897 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL29517940 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL29517807 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL2993922 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL29518480 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL524404 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL29517882 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL22231674 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR
SCHEMBL29517793 0.94 LMNA (0.47) LMNAEGLN1ALKBH5SUCNR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966161-A1 METHOD FOR OBTAINING METAL OXIDES SUPPORTED ON MESOPOROUS SILICA PARTICLES Technische Universität Berlin (DE) 2022-03-16 EP disclosed