Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 7/20 | 0.45 |
| ▸ | NPY1R | P25929 | 5/20 | 0.45 |
| ▸ | NPY2R | P49146 | 4/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.45 |
| ▸ | GLP1R | P43220 | 3/20 | 0.45 |
| ▸ | SCTR | P47872 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519643 | 0.94 | BACE1 (0.49) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29511116 | 0.93 | FNTA (0.47) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL30956349 | 0.92 | GLP1R (0.48) | GLP1RSCTRKLK7C5AR1APLNR | |
| SCHEMBL30952096 | 0.91 | NPY4R (0.43) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL31387094 | 0.90 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29519652 | 0.90 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL30589457 | 0.90 | C5AR1 (0.45) | NPY4RNPY1RNPY2RNPY5RGLP1R | |
| SCHEMBL29958548 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RC5AR1 | |
| SCHEMBL31190176 | 0.90 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5RFOLH1 | |
| SCHEMBL30956346 | 0.90 | GLP1R (0.50) | GLP1RSCTRMC4RKLK7C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124612-A1 | MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES | MEDIMMUNE LLC | 2024-04-18 | — | — | US | disclosed |
| US-11767369-B2 | Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties | MEDIMMUNE, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-106413750-B | Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties | 免疫医疗有限责任公司 | 2022-04-29 | — | — | CN | disclosed |