Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29015219 | 1.00 | MAPT (0.55) | MAPTLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL30401215 | 0.83 | CYP1A2 (0.51) | MAPTALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29880371 | 0.83 | CYP1A2 (0.51) | MAPTALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL23747775 | 0.82 | MAPT (0.64) | MAPTLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL10271717 | 0.81 | KMT2A (0.47) | MAPTLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL6805105 | 0.81 | HTT (0.44) | LMNAALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6805108 | 0.81 | HTT (0.44) | LMNAALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL161867 | 0.80 | LMNA (0.56) | MAPTLMNAALDH1A1KMT2AKCNJ1 | |
| SCHEMBL26188701 | 0.79 | MAPT (0.62) | MAPTLMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL28811683 | 0.77 | MAPT (0.63) | MAPTLMNAALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022067566-A1 | PYRIMIDINEDIONE COMPOUND CONTAINING SATURATED OXYGEN-CONTAINING HETEROCYCLIC GROUP AND USE THEREOF | 广东东阳光药业有限公司 | 2022-04-07 | — | — | WO | disclosed |