Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | TLR2 | O60603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557254 | 1.00 | CYP2B6 (0.43) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL30405223 | 0.98 | CYP2B6 (0.43) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL1896984 | 0.82 | CA1 (0.44) | CYP2B6CA1CA9MEN1LMNA | |
| SCHEMBL15676323 | 0.77 | ERN1 (0.39) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL277664 | 0.77 | CYP2B6 (0.46) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL12043463 | 0.73 | CYP2B6 (0.42) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL11192919 | 0.73 | CYP2B6 (0.42) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL31301918 | 0.73 | CYP2B6 (0.42) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL2009438 | 0.73 | CYP2B6 (0.42) | CYP2B6CA1CA9CYP1A1CYP1A2 | |
| SCHEMBL3076682 | 0.73 | CYP2B6 (0.42) | CYP2B6CA1CA9CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11462305-B2 | Biomarkers for detecting colorectal cancer or adenoma and methods thereof | Precogify Pharmaceutical China Co., Ltd. (CN) | 2022-10-04 | — | — | US | disclosed |
| US-20220108777-A1 | BIOMARKERS FOR DETECTING COLORECTAL CANCER OR ADENOMA AND METHODS THEREOF | Precogify Pharmaceutical China Co., Ltd. (CN) | 2022-04-07 | — | — | US | disclosed |