Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557254 | 0.82 | CYP2B6 (0.43) | CA1CA9MEN1LMNATHRB | |
| SCHEMBL29519680 | 0.82 | CYP2B6 (0.43) | CA1CA9MEN1LMNATHRB | |
| Hydrochloric Acid SCHEMBL30405223 | 0.81 | CYP2B6 (0.43) | CA1CA9MEN1LMNATHRB | |
| SCHEMBL4403285 | 0.71 | MEN1 (0.38) | CA1MEN1LMNATHRBBLM | |
| SCHEMBL1012582 | 0.70 | KDM4E (0.61) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL6851157 | 0.68 | TDP1 (0.46) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL2859416 | 0.67 | MEN1 (0.41) | CA1MEN1LMNATHRBBLM | |
| SCHEMBL29561776 | 0.67 | MEN1 (0.41) | CA1MEN1LMNATHRBBLM | |
| SCHEMBL1253612 | 0.67 | KDM4E (0.53) | MEN1LMNATHRBBLMKMT2A | |
| SCHEMBL734868 | 0.67 | PARP1 (0.53) | MEN1LMNATHRBBLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322505-A1 | 1-ADAMANTYLAZETIDIN-2-ONE DERIVATIVE AND PHARMACEUTICAL PREPARATION COMPRISING SAME | Kowa Company, Ltd. (JP) | 2011-05-18 | — | — | EP | disclosed |