Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 19/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754809 | 1.00 | BTK (0.48) | BTKEGFR | |
| SCHEMBL29519980 | 0.80 | BTK (0.46) | BTK | |
| SCHEMBL16754896 | 0.80 | BTK (0.46) | BTK | |
| SCHEMBL1725875 | 0.78 | BTK (0.48) | BTK | |
| SCHEMBL31077836 | 0.77 | BTK (0.62) | BTK | |
| SCHEMBL1725249 | 0.77 | BTK (0.62) | BTK | |
| SCHEMBL29911628 | 0.76 | BTK (0.56) | BTK | |
| SCHEMBL20752427 | 0.74 | BTK (0.47) | BTK | |
| SCHEMBL24966693 | 0.73 | BTK (0.48) | BTK | |
| SCHEMBL32667552 | 0.73 | BTK (0.48) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172056-B | Aminopyrimidine derivatives | 诺华股份有限公司 | 2022-04-19 | — | — | CN | disclosed |