Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CD69 | Q07108 | 1/20 | 0.39 |
| ▸ | YES1 | P07947 | 1/20 | 0.37 |
| ▸ | FGR | P09769 | 1/20 | 0.37 |
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | BMX | P51813 | 1/20 | 0.37 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20365206 | 0.82 | BTK (0.43) | BTKKCNH2CD69 | |
| SCHEMBL20371778 | 0.78 | BTK (0.41) | BTKKCNH2CD69 | |
| SCHEMBL20867825 | 0.77 | BTK (0.39) | BTKKCNH2CD69YES1FGR | |
| SCHEMBL26800825 | 0.76 | BRD9 (0.39) | — | |
| SCHEMBL25898037 | 0.75 | TAF1 (0.38) | — | |
| SCHEMBL16754809 | 0.74 | BTK (0.48) | BTK | |
| SCHEMBL29519783 | 0.74 | BTK (0.48) | BTK | |
| SCHEMBL16786047 | 0.72 | HTR6 (0.37) | BTK | |
| SCHEMBL24966693 | 0.72 | BTK (0.48) | BTK | |
| Hydrochloric Acid SCHEMBL16763471 | 0.72 | BTK (0.36) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3444251-A1 | BIARYL COMPOUNDS USEFUL FOR THE TREATMENT OF HUMAN DISEASES IN ONCOLOGY, NEUROLOGY AND IMMUNOLOGY | Biogen MA Inc. (US) | 2019-02-20 | — | — | EP | disclosed |