SCHEMBL29519897

SCHEMBL29519897

O=C1CNC(=O)[C@@H](CS)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)CN1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 8/20 0.52
OPRD1 P41143 8/20 0.52
OPRK1 P41145 4/20 0.52
CXCR4 P61073 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519649 1.00 OPRM1 (0.52) OPRM1OPRD1OPRK1CXCR4
SCHEMBL29519776 1.00 OPRM1 (0.52) OPRM1OPRD1OPRK1CXCR4
SCHEMBL30637559 0.94 OPRM1 (0.55) OPRM1OPRD1OPRK1CXCR4
SCHEMBL30637590 0.94 OPRM1 (0.55) OPRM1OPRD1OPRK1CXCR4
SCHEMBL30637487 0.94 OPRM1 (0.55) OPRM1OPRD1OPRK1CXCR4
SCHEMBL30637599 0.94 OPRM1 (0.55) OPRM1OPRD1OPRK1CXCR4
SCHEMBL29520027 0.89 OPRM1 (0.46) OPRM1OPRD1OPRK1CXCR4
SCHEMBL12148795 0.86 HDAC8 (0.54) OPRM1OPRD1OPRK1CXCR4
SCHEMBL8135311 0.86 HDAC8 (0.54) OPRM1OPRD1OPRK1CXCR4
SCHEMBL3205012 0.86 HRH3 (0.53) OPRM1OPRD1OPRK1CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US claimed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN claimed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO claimed
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND SHAANXI MICOT TECHNOLOGY CO., LTD. (CN) 2023-10-19 US disclosed
CN-115087662-B Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2023-09-26 CN disclosed
CN-115087662-A Bispecific fusion polypeptide compounds 陕西麦科奥特科技有限公司 2022-09-20 CN disclosed
WO-2022052471-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND 陕西麦科奥特科技有限公司 2022-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331779-A1 BISPECIFIC FUSION POLYPEPTIDE COMPOUND CALCR, BID, CASR OPRM1 379/4885OPRD1 315/4885OPRK1 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.