Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ceruletide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR known ✓ | P32238 | 8/20 | 0.69 |
| ▸ | CCKBR | P32239 | 14/20 | 0.69 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ceruletide SCHEMBL23148172 | 0.99 | CCKBR (0.69) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL8963088 | 0.98 | CCKBR (0.67) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL122757 | 0.98 | CCKBR (0.66) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL6836302 | 0.95 | CCKBR (0.62) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL511740 | 0.94 | CCKBR (0.62) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL20774551 | 0.91 | CCKBR (0.58) | CCKBRCCKARIL23R | |
| SCHEMBL11217188 | 0.90 | CCKBR (0.64) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL20775134 | 0.86 | CCKBR (0.52) | CCKBRCCKARIL23R | |
| Caerulin SCHEMBL29597850 | 0.85 | CCKBR (0.80) | CCKBRCCKARIL23R | |
| Ceruletide SCHEMBL8200799 | 0.85 | CCKBR (0.50) | CCKBRCCKARIL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2612 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124148-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | BHAMIS RES LABORATORY PVT LTD (IN) | 2026-05-07 | — | — | US | claimed |
| US-12533321-B2 | Polypeptide formulations for oral delivery | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2026-01-27 | — | — | US | claimed |
| EP-4601623-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2025-08-20 | — | — | EP | claimed |
| US-20240398819-A1 | UTILITY OF VITAMIN D, FOLIC ACID AND NADH TO IMPROVE LIGAMENT INJURY PREVENTION CHARACTERISTICS | RHODE ISLAND HOSPITAL | 2024-12-05 | — | — | US | claimed |
| US-20240325307-A1 | HIGH DENSITY PEPTIDE POLYMERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-10-03 | — | — | US | claimed |
| EP-4374913-A2 | NOVEL HUMAN SERUM ALBUMIN MUTANT | JCR Pharmaceuticals Co., Ltd. (JP) | 2024-05-29 | — | — | EP | claimed |
| WO-2024079739-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2024-04-18 | — | — | WO | claimed |
| US-20240122860-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2024-04-18 | — | — | US | claimed |
| US-20240122847-A1 | ORAL POLYPEPTIDE FORMULATIONS | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2024-04-18 | — | — | US | claimed |
| WO-2024079738-A1 | ORAL POLYPEPTIDE FORMULATIONS | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2024-04-18 | — | — | WO | claimed |
| US-4670419-A | POLYPEPTIDE AND CYCLODEXTRIN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-06-02 | — | — | US | claimed |
| US-4659696-A | MIXTURE OF POLYPEPTIDE AND CYCLODEXTRIN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-21 | — | — | US | claimed |
| EP-0215697-A2 | Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments | MERCK & CO. INC. (US) | 1987-03-25 | — | — | EP | claimed |
| EP-0214898-A2 | Choline esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities | MERCK & CO. INC. (US) | 1987-03-18 | — | — | EP | claimed |
| EP-0095806-B1 | A PROCESS FOR PREPARING CAERULEIN | SHIONOGI & CO., LTD. (JP) | 1987-01-07 | — | — | EP | claimed |
| US-4552865-A | CAERULEIN, SCHIZOPHRENIA | SHIONOGI & CO., LTD. (JP) | 1985-11-12 | — | — | US | claimed |
| EP-0106282-A2 | Production of caerulein intermediate | Shionogi & Co., Ltd. (JP) | 1984-04-25 | — | — | EP | claimed |
| US-4444682-A | OF HYDROXY AMINO ACIDS OR PEPTIDES CONTAINING SAME | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1984-04-24 | — | — | US | claimed |
| EP-0095806-A1 | A process for preparing caerulein | SHIONOGI & CO., LTD. (JP) | 1983-12-07 | — | — | EP | claimed |
| US-4351829-A | Use of polypeptides as analgesic drugs | FARMITALIA CARLO ERBA SPA (IT) | 1982-09-28 | — | — | US | claimed |