SCHEMBL29520661

SCHEMBL29520661

CCCc1cc(=O)oc2c(C(=O)CC(C)C)c(O)c(CC=C(C)C)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 18/20 1.00
EPAS1 Q99814 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29934508 0.86 HIF1A (1.00) HIF1AEPAS1
Isomammeisin SCHEMBL6914103 0.80 HIF1A (1.00) HIF1AEPAS1
Mammeisin SCHEMBL6913744 0.74 HIF1A (1.00) HIF1AEPAS1
Mammeisin SCHEMBL31237557 0.74 HIF1A (1.00) HIF1AEPAS1
SCHEMBL30969426 0.74 HIF1A (0.70) HIF1AEPAS1
SCHEMBL31580177 0.72 FFAR1 (0.55) HIF1AEPAS1
SCHEMBL6125217 0.72 HIF1A (0.55) HIF1AEPAS1
SCHEMBL30377279 0.71 HIF1A (0.78) HIF1AEPAS1
Isomesuol SCHEMBL16367909 0.70 HIF1A (0.84) HIF1AEPAS1
SCHEMBL30100963 0.69 FFAR1 (0.64) HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114258430-A Compositions and methods for TCR reprogramming using fusion proteins T细胞受体治疗公司 2022-03-29 CN disclosed