SCHEMBL29934508

SCHEMBL29934508

CCCc1cc(=O)oc2c(C(=O)C(C)CC)c(O)c(CC=C(C)C)c(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 19/20 1.00
EPAS1 Q99814 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29520661 0.86 HIF1A (1.00) HIF1AEPAS1
SCHEMBL30377279 0.85 HIF1A (0.78) HIF1AEPAS1
SCHEMBL31237267 0.82 HIF1A (1.00) HIF1AEPAS1
SCHEMBL6907224 0.82 HIF1A (1.00) HIF1AEPAS1
SCHEMBL29517025 0.77 HIF1A (0.70) HIF1AEPAS1
SCHEMBL6914633 0.74 HIF1A (1.00) HIF1AEPAS1
Isomesuol SCHEMBL16367909 0.74 HIF1A (0.84) HIF1AEPAS1
SCHEMBL24075656 0.74 HIF1A (0.56) HIF1AEPAS1
SCHEMBL30969426 0.72 HIF1A (0.70) HIF1AEPAS1
Achyrofuran SCHEMBL505137 0.71 HIF1A (0.57) HIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220291237-A1 Gene Expression Inflammatory Age and Its Uses Edifice Health, Inc. (US) 2022-09-15 US disclosed