SCHEMBL29520754

SCHEMBL29520754

Nc1cccc(N(c2ccc(N(c3cccc(N)c3)c3cccc(N)c3)cc2)c2cccc(N)c2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
CYP3A4 P08684 4/20 0.58
KDM4E B2RXH2 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
MAPT P10636 3/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2D6 P10635 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
CASP1 P29466 1/20 0.52
RECQL P46063 1/20 0.52
SYK P43405 1/20 0.46
ENPP2 Q13822 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26185692 1.00 ALDH1A1 (0.58) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL2441988 0.95 CYP3A4 (0.58) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL29596268 0.93 TDP1 (0.62) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL5293932 0.93 TDP1 (0.62) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL8605466 0.93 TDP1 (0.62) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL18850247 0.91 CYP3A4 (0.75) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL8563717 0.89 ALDH1A1 (0.48) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL29320825 0.88 KDM4E (0.57) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL9821741 0.85 ALDH1A1 (0.73) ALDH1A1CYP3A4KDM4ETDP1MAPT
SCHEMBL15481639 0.84 ALDH1A1 (0.44) ALDH1A1CYP3A4KDM4ETDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022054552-A1 POLYMETALLOXANE-CONTAINING COMPOSITION, CURED BODY, MEMBER, ELECTRONIC COMPONENT, AND FIBER 東レ株式会社 2022-03-17 WO disclosed