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Sugi Predict / Compounds / SCHEMBL29521627

SCHEMBL29521627

SCHEMBL29521627

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(N)=O)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O)C(C)C)[C@@H](C)O

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.58
▸ CALCR P30988 4/20 0.58
▸ CRHR1 P34998 1/20 0.56
▸ CRHR2 Q13324 1/20 0.56
▸ OPRM1 P35372 1/20 0.54
▸ OPRD1 P41143 1/20 0.54
▸ OPRK1 P41145 1/20 0.54
▸ F2 P00734 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521428 0.96 CALCR (0.58) GLP1RCALCRCRHR1CRHR2F2
SCHEMBL30662034 0.91 GLP1R (0.53) GLP1RCALCROPRD1F2
SCHEMBL30361661 0.90 GLP1R (0.62) GLP1RCALCR
SCHEMBL31005062 0.89 GLP1R (0.55) GLP1RCALCRCRHR1CRHR2OPRM1
SCHEMBL38665153 0.89 CALCR (0.51) GLP1RCALCRCRHR1CRHR2F2
SCHEMBL29597500 0.89 OPRM1 (0.56) GLP1RCALCRCRHR1CRHR2OPRM1
SCHEMBL29597233 0.89 OPRM1 (0.56) GLP1RCALCRCRHR1CRHR2OPRM1
SCHEMBL30510653 0.89 GLP1R (0.51) GLP1RCALCROPRM1OPRD1OPRK1
SCHEMBL31454237 0.89 GLP1R (0.68) GLP1RCALCRCRHR1CRHR2
SCHEMBL30874946 0.89 GLP1R (0.52) GLP1RCALCRCRHR1CRHR2OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547703-A1 AMYLIN RECEPTOR (HAMY3R) AGONISTS WITH IMPROVED CHEMICAL STABILITY Gubra A/S (DK) 2025-05-07 — — EP disclosed
WO-2024003359-A1 AMYLIN RECEPTOR (hAMY3R) AGONISTS WITH IMPROVED CHEMICAL STABILITY Gubra A/S (DK) 2024-01-04 — — WO disclosed
EP-4021929-A1 HAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (HAMY3R) POTENCY Gubra ApS (DK) 2022-07-06 — — EP disclosed
WO-2022063925-A1 HAM15-52 ANALOGUES WITH IMPROVED AMYLIN RECEPTOR (HAMY3R) POTENCY GUBRA APS (DK) 2022-03-31 — — WO disclosed
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