SCHEMBL29522639

SCHEMBL29522639

BrCCCCCCOc1ccc(C(=C(c2ccccc2)c2ccc(OCCCCCCBr)cc2)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.57
CYP19A1 P11511 2/20 0.57
ESR2 Q92731 1/20 0.57
PPARA Q07869 1/20 0.53
PSMB1 P20618 1/20 0.53
PSMB5 P28074 1/20 0.53
KCNA3 P22001 1/20 0.52
KCNH2 Q12809 3/20 0.49
CHRM2 P08172 3/20 0.49
ADRA2A P08913 3/20 0.49
SLC6A2 P23975 3/20 0.49
SLC6A4 P31645 3/20 0.49
DRD3 P35462 3/20 0.49
SLC6A3 Q01959 3/20 0.49
EBP Q15125 2/20 0.49
SIGMAR1 Q99720 2/20 0.49
ADORA3 P0DMS8 2/20 0.49
CHRM1 P11229 2/20 0.49
PTGS1 P23219 2/20 0.49
HTR6 P50406 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024560 0.98 ESR1 (0.58) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL12659242 0.98 ESR1 (0.58) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL30879984 0.95 ESR1 (0.58) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL16414415 0.93 PRMT1 (0.55) KCNH2CHRM2ADRA2ASLC6A2SLC6A4
SCHEMBL79978 0.90 ESRRG (0.52) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL69279 0.89 ESR1 (0.60) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL69280 0.89 ESR1 (0.60) ESR1CYP19A1ESR2PPARAPSMB1
SCHEMBL9360444 0.86 PPARA (0.71) PPARAKDM4EMAPTGAAPKM
SCHEMBL9361207 0.86 PPARA (0.71) PPARAKDM4EMAPTGAAPKM
SCHEMBL9365095 0.86 PPARA (0.71) PPARAKDM4EMAPTGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114025871-A System and method for producing nanoparticles 新加坡国立大学 2022-02-08 CN disclosed