Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.55 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | EBP | Q15125 | 3/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69279 | 1.00 | ESR1 (0.60) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL67013 | 0.92 | ESR1 (0.49) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL12659242 | 0.91 | ESR1 (0.58) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL28024560 | 0.91 | ESR1 (0.58) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL30879984 | 0.91 | ESR1 (0.58) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL29522639 | 0.89 | ESR1 (0.57) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL7654138 | 0.85 | CYP19A1 (0.74) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL11268363 | 0.85 | CYP19A1 (0.74) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL10796202 | 0.85 | CYP19A1 (0.74) | ESR1CYP19A1ESR2PSMB1PSMB5 | |
| SCHEMBL6338785 | 0.85 | GAA (0.72) | PKMGAAMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518921-B2 | Silica nanoparticles with aggregation induced emission characteristics as fluorescent bioprobe for intracellular imaging and protein carrier | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2016-12-13 | — | — | US | disclosed |
| US-9518921-B2 | Silica nanoparticles with aggregation induced emission characteristics as fluorescent bioprobe for intracellular imaging and protein carrier | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2016-12-13 | — | — | US | disclosed |
| US-9518921-B2 | Silica nanoparticles with aggregation induced emission characteristics as fluorescent bioprobe for intracellular imaging and protein carrier | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2016-12-13 | — | — | US | disclosed |
| US-9279806-B2 | Water-soluble AIE luminogens for monitoring and retardation of fibrillation of amyloid proteins | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-03-08 | — | — | US | disclosed |
| US-20150031607-A1 | WATER-SOLUBLE AIE LUMINOGENS FOR MONITORING AND RETARDATION OF FIBRILLATION OF AMYLOID PROTEINS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-01-29 | — | — | US | disclosed |
| US-20140255696-A1 | Biotin-Decorated Fluorescent Silica Nanoparticles With Aggregation-Induced Emission for Tumor Cell Targeting and Long-Term Tumor Cell Tracking | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-09-11 | — | — | US | disclosed |
| US-20140255696-A1 | Biotin-Decorated Fluorescent Silica Nanoparticles With Aggregation-Induced Emission for Tumor Cell Targeting and Long-Term Tumor Cell Tracking | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-09-11 | — | — | US | disclosed |
| US-20140255696-A1 | Biotin-Decorated Fluorescent Silica Nanoparticles With Aggregation-Induced Emission for Tumor Cell Targeting and Long-Term Tumor Cell Tracking | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-09-11 | — | — | US | disclosed |
| US-8679738-B2 | Water-soluble AIE luminogen for monitoring and retardation of amyloid fibrillation of insulin | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2014-03-25 | — | — | US | disclosed |
| US-20130210047-A1 | SILICA NANOPARTICLES WITH AGGREGATION INDUCED EMISSION CHARACTERISTICS AS FLUORESCENT BIOPROBE FOR INTRACELLULAR IMAGING AND PROTEIN CARRIER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-08-15 | — | — | US | disclosed |
| US-20130210047-A1 | SILICA NANOPARTICLES WITH AGGREGATION INDUCED EMISSION CHARACTERISTICS AS FLUORESCENT BIOPROBE FOR INTRACELLULAR IMAGING AND PROTEIN CARRIER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-08-15 | — | — | US | disclosed |
| US-20130210047-A1 | SILICA NANOPARTICLES WITH AGGREGATION INDUCED EMISSION CHARACTERISTICS AS FLUORESCENT BIOPROBE FOR INTRACELLULAR IMAGING AND PROTEIN CARRIER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-08-15 | — | — | US | disclosed |
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2012-07-05 | — | — | US | disclosed |
| US-8129111-B2 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-03-06 | — | — | US | disclosed |
| US-7939613-B2 | Probes/sensors for biomacromolecules; films; cosmetics | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2011-05-10 | — | — | US | disclosed |
| US-20100009362-A1 | Fluorescent water-soluable conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-01-14 | — | — | US | disclosed |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172296-A1 | WATER-SOLUBLE AIE LUMINOGEN FOR MONITORING AND RETARDATION OF AMYLOID FIBRILLATION OF INSULIN | IAPP, IGF2BP1, IGF2BP2 | ESR1 1506/4885CYP19A1 869/4885ESR2 2995/4885 |
| US-20080220407-A1 | Fluorescent water-soluble conjugated polyene compounds that exhibit aggregation induced emission and methods of making and using same | FUS, CD63, EPCAM | ESR1 3545/4885CYP19A1 3349/4885ESR2 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.