Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23824890 | 0.90 | KMT2A (0.53) | ALDH1A1L3MBTL1MAPTRAB9ACA12 | |
| SCHEMBL5746395 | 0.80 | POLB (0.55) | ALDH1A1MAPTNPSR1POLBLMNA | |
| SCHEMBL5746398 | 0.80 | POLB (0.55) | ALDH1A1MAPTNPSR1POLBLMNA | |
| SCHEMBL10772213 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL29904957 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL10772216 | 0.80 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL12515611 | 0.79 | F2 (0.51) | ALDH1A1SMN1; SMN2L3MBTL1MAPTPOLB | |
| SCHEMBL18343542 | 0.78 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPTNPSR1POLB | |
| SCHEMBL10047320 | 0.78 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPTRAB9APOLB | |
| SCHEMBL31556700 | 0.78 | POLB (0.52) | ALDH1A1SMN1; SMN2MAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025008012-A1 | PYRROLOQUINOLINES AND THEIR USE AS TUBULINE ASSEMBLY INHIBITORS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2025-01-09 | — | — | WO | disclosed |
| US-20220098155-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (INSA) (FR) | 2022-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220098155-A1 | NOVEL PATHWAY FOR THE SYNTHESIS OF DIAZIRINES, THAT MAY OR MAY NOT BE ENRICHED IN NITROGEN-15 | SSTR5, SLC6A15, SLC1A5 | ALDH1A1 2836/4885SMN1; SMN2 3683/4885L3MBTL1 3841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.