Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.53 |
| ▸ | MDM4 | O15151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5405533 | 0.84 | MAPT (0.56) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL5405527 | 0.84 | MAPT (0.56) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL17737129 | 0.82 | MAPT (0.51) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL28242823 | 0.78 | MAPT (0.51) | MAPTLMNAMDM2MDM4KMT2A | |
| SCHEMBL3168058 | 0.77 | KMT2A (0.59) | LMNAKMT2AMMP8ALDH1A1GAA | |
| SCHEMBL20274587 | 0.77 | KMT2A (0.59) | LMNAKMT2AMMP8ALDH1A1GAA | |
| SCHEMBL9114061 | 0.76 | CYP2C19 (0.67) | LMNAKMT2AALDH1A1 | |
| SCHEMBL27625128 | 0.76 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL174166 | 0.75 | KMT2A (0.60) | MAPTLMNAKMT2AALDH1A1GAA | |
| SCHEMBL18381730 | 0.75 | KMT2A (0.60) | MAPTLMNAKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11932601-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2022-09-01 | — | — | US | disclosed |
| US-11242319-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2022-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11242319-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | MAPT 2758/4885LMNA 4878/4885MDM2 1615/4885 |
| US-11932601-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | MAPT 2758/4885LMNA 4878/4885MDM2 1615/4885 |
| US-20220274926-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | MAPT 2758/4885LMNA 4878/4885MDM2 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.