Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22787167 | 1.00 | LMNA (0.37) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22787129 | 1.00 | LMNA (0.37) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22773547 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22773545 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22787131 | 0.84 | LMNA (0.35) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22787135 | 0.83 | LMNA (0.32) | LMNASMN1; SMN2HTT | |
| SCHEMBL22787195 | 0.83 | LMNA (0.39) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22773528 | 0.83 | KMT2A (0.41) | LMNAHTTKDM4EALDH1A1GAA | |
| SCHEMBL22787130 | 0.83 | LMNA (0.39) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL22787185 | 0.83 | KMT2A (0.41) | LMNAHTTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983406-A1 | UNSATURATED HETEROCYCLOALKYL AND HETEROAROMATIC ACYL HYDRAZONE LINKERS, METHODS AND USES THEREOF | Ontario Institute for Cancer Research (OICR) (CA) | 2022-04-20 | — | — | EP | disclosed |