Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009026 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL6804031 | 0.98 | TSHR (0.64) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL30469335 | 0.98 | TSHR (0.64) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL7838339 | 0.98 | LMNA (0.64) | TSHRLMNAALDH1A1NPC1RAB9A | |
| Iodide SCHEMBL27148619 | 0.98 | TSHR (0.64) | TSHRLMNAALDH1A1NPC1RAB9A | |
| Formaldehyde SCHEMBL28138818 | 0.96 | TSHR (0.61) | TSHRLMNAALDH1A1NPC1RAB9A | |
| Dinitrophenylene SCHEMBL27704073 | 0.93 | TSHR (0.77) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL6738366 | 0.93 | TSHR (0.76) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL936227 | 0.92 | LMNA (0.57) | TSHRLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL28471286 | 0.91 | TSHR (0.73) | TSHRLMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507252-B | Novel method for synthesizing arylsilane compound | 广西大学 | 2023-10-27 | — | — | CN | claimed |
| US-20250268926-A1 | METHOD AND COMPOSITION FOR TREATING, ALLEVIATING OR PREVENTING A DISEASE OR CONDITION CAUSED BY AIR POLLUTANT | HONG KONG BAPTIST UNIVERSITY (CN) | 2025-08-28 | — | — | US | disclosed |
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | DONG-A SOCIO HOLDINGS CO., LTD. (KR) | 2025-01-14 | — | — | US | disclosed |
| CN-118146102-A | Method for synthesizing diaryl amine or triarylamine by using nitroaromatic hydrocarbon as raw material | 广西大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-117164879-A | Phenyl-1, 3, 5-tri-3-pyridine formaldehyde imine covalent organic framework material matched with divalent transition metal, and preparation method and catalytic application thereof | 南京工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-114507252-B | Novel method for synthesizing arylsilane compound | 广西大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-116635021-A | Opioid-free compositions for narcotics applications and related methods and systems | 威培沃克斯护理麻醉公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-115838372-A | Triphenylethylene derivative and organic electroluminescent device containing same | 广东省大湾区华南理工大学聚集诱导发光高等研究院 | 2023-03-24 | — | — | CN | disclosed |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | DONG A SOCIO HOLDINGS CO LTD (KR) | 2023-01-05 | — | — | US | disclosed |
| CN-115006537-A | Compositions and uses of alpha-adrenergic agents | 利维申制药有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114507252-A | Synthesis method of novel aryl silane compound | 广西大学 | 2022-05-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195446-B2 | Heteroaryl compounds and their use as therapeutic drugs | MERTK, ERBB2, SRC | TSHR 1878/4885LMNA 3611/4885ALDH1A1 3115/4885 |
| US-20230002353-A1 | HETEROARYL COMPOUNDS AND THEIR USE AS THERAPEUTIC DRUGS | MERTK, ERBB2, SRC | TSHR 1878/4885LMNA 3611/4885ALDH1A1 3115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.