SCHEMBL29526403

SCHEMBL29526403

N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.56
GSTK1 Q9Y2Q3 1/20 0.56
GLO1 Q04760 2/20 0.49
DPP4 P27487 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
GRM8 O00222 1/20 0.40
GRM6 O15303 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GSR P00390 1/20 0.40
CYP1A2 P05177 1/20 0.40
GRIK1 P39086 1/20 0.40
GRM5 P41594 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
SLC1A3 P43003 1/20 0.40
SLC1A2 P43004 1/20 0.40
SLC1A1 P43005 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526252 1.00 PTGS1 (0.56) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29526351 0.97 PTGS1 (0.53) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29597665 0.93 PTGS1 (0.52) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29526261 0.93 PTGS1 (0.51) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29526001 0.92 PTGS1 (0.50) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL22316501 0.91 PTGS1 (0.58) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL22111145 0.91 PTGS1 (0.58) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29526128 0.90 PTGS1 (0.51) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL14774754 0.90 PTGS1 (0.50) PTGS1GSTK1GLO1DPP4DPP8
SCHEMBL29526446 0.90 PTGS1 (0.52) PTGS1GSTK1GLO1DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240002472-A1 ULINASTATIN POLYPEPTIDES DiaMedica USA Inc. 2024-01-04 US claimed
US-11725043-B2 Ulinastatin polypeptides DiaMedica USA Inc. (US) 2023-08-15 US claimed
EP-4114428-A1 ULINASTATIN POLYPEPTIDES Diamedica USA Inc. (US) 2023-01-11 EP claimed
CN-115515616-A Ulinastatin polypeptide 代阿麦迪卡美国股份有限公司 2022-12-23 CN claimed
JP-2026020254-A ダイアメディカ ユーエスエー インコーポレイテッド 2026-02-06 JP disclosed
US-20240002472-A1 ULINASTATIN POLYPEPTIDES DiaMedica USA Inc. 2024-01-04 US disclosed
EP-4284406-A1 ULINASTATIN POLYPEPTIDES FOR TREATING DISEASES Diamedica USA Inc. (US) 2023-12-06 EP disclosed
CN-117015390-A Ulinastat Ding Duotai for treating diseases 代阿麦迪卡美国股份有限公司 2023-11-07 CN disclosed
US-11725043-B2 Ulinastatin polypeptides DiaMedica USA Inc. (US) 2023-08-15 US disclosed
JP-2023516422-A ダイアメディカ ユーエスエー インコーポレイテッド 2023-04-19 JP disclosed
EP-4114428-A1 ULINASTATIN POLYPEPTIDES Diamedica USA Inc. (US) 2023-01-11 EP disclosed
CN-115515616-A Ulinastatin polypeptide 代阿麦迪卡美国股份有限公司 2022-12-23 CN disclosed
US-20220242932-A1 ULINASTATIN POLYPEPTIDES FOR TREATING DISEASES DiaMedica USA Inc. 2022-08-04 US disclosed
WO-2022165031-A1 ULINASTATIN POLYPEPTIDES FOR TREATING DISEASES DiaMedica USA Inc. (US) 2022-08-04 WO disclosed
CN-114269774-A Appetite suppressant compounds IP2IPO创新有限公司 2022-04-01 CN disclosed