Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22316501 | 1.00 | PTGS1 (0.58) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL22111140 | 0.93 | PTGS1 (0.53) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29586584 | 0.92 | PTGS1 (0.53) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29526403 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29526252 | 0.91 | PTGS1 (0.56) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29695437 | 0.90 | PTGS1 (0.51) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL30099681 | 0.90 | PTGS1 (0.51) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL30292792 | 0.89 | PTGS1 (0.52) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL173099 | 0.89 | PTGS1 (0.55) | PTGS1GSTK1GLO1DPP4DPP8 | |
| SCHEMBL29384215 | 0.89 | PTGS1 (0.55) | PTGS1GSTK1GLO1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666788-A1 | HEMIASTERLIN DERIVATIVES AND ANTIBODY-DRUG CONJUGATES INCLUDING SAME | Sumitomo Dainippon Pharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |