⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070762 | 0.95 | KDM4E (0.75) | — | |
| SCHEMBL12445967 | 0.92 | KDM4E (0.80) | — | |
| SCHEMBL22197991 | 0.92 | KDM4E (0.80) | — | |
| SCHEMBL12281920 | 0.92 | KDM4E (0.80) | — | |
| SCHEMBL12282003 | 0.92 | KDM4E (0.80) | — | |
| SCHEMBL24508761 | 0.92 | KDM4E (0.80) | — | |
| SCHEMBL13867482 | 0.91 | PAOX (0.67) | — | |
| SCHEMBL1900471 | 0.89 | KDM4E (0.82) | — | |
| SCHEMBL12014973 | 0.86 | KDM4E (0.70) | — | |
| SCHEMBL26279564 | 0.84 | MAPK1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822044-A | A kind of synthetic method of 1,2- dimethyl -1,4,5,6- tetrahydropyrimidine | 西安万德科技有限公司 | 2018-11-16 | — | — | CN | claimed |
| EP-2121600-B1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2012-07-18 | — | — | EP | claimed |
| US-20100093703-A1 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-15 | — | — | US | claimed |
| EP-2121600-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | Boehringer Ingelheim International GmbH (DE) | 2009-11-25 | — | — | EP | claimed |
| WO-2008099000-A2 | SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-21 | — | — | WO | claimed |
| WO-2023072974-A1 | TRICYCLIC HETEROCYCLES | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2022269532-A1 | TRIAZINE DERIVATIVES FOR THE TREATMENT OF TUMOURS AND NEURODEGENERATIVE DISORDERS | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022264069-A1 | METHOD FOR PREPARING FLUOROPHORE- AND CHROMOPHORE-CONTAINING CONJUGATES FOR VISUAL DETECTION OF ANALYTE MOLECULES | Sony Group Corporation (JP) | 2022-12-22 | — | — | WO | disclosed |
| CN-110156697-B | Synthetic method of 1,2-dimethyl-1,4,5,6-tetrahydropyrimidine | 常州沃腾化工科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3929185-A1 | NITROGEN-CONTAINING FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| WO-2021224291-A1 | TRICYCLIC HETEROCYCLES USEFUL AS TEAD BINDERS | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | WO | disclosed |
| EP-0002286-B1 | LUBRICANT OR FUEL | ROHM AND HAAS COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4411804-A | CONTAINING GRAPHITE, MOLYBDENUM DISULFIDE, OR ZINC OXIDE AND FLOW CONTROL AGENT | ATLANTIC RICHFIELD COMPANY (US) | 1983-10-25 | — | — | US | disclosed |
| US-4292185-A | COMPRISING A DIENE-MODIFIED MONOOLEFINIC POLYMER REACTED WITH CHLOROSULFONYL ISOCYANATE AND THEN WITH AN AMINE | ROHM AND HAAS COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4160739-A | Polyolefinic copolymer additives for lubricants and fuels | ROHM AND HAAS COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| EP-0002286-A2 | Lubricant or fuel | ROHM AND HAAS COMPANY (US) | 1979-06-13 | — | — | EP | disclosed |
| US-4136040-A | ALSO INCLUDING A NITROGEN CONTAINING MIXED ESTER OF AN OLEFIN ALPHA, B-UNSATURATED ACID OR ANHYDRIDE COPOLYMER | ATLANTIC RICHFIELD COMPANY (US) | 1979-01-23 | — | — | US | disclosed |
| US-3951965-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3933761-A | INTERPOLYMERS | THE LUBRIZOL CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |