Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 16/20 | 0.62 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22772542 | 1.00 | GRIN2B (0.62) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL29527511 | 0.89 | GRIN2B (0.61) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22772486 | 0.89 | GRIN2B (0.61) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22772548 | 0.88 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL29526782 | 0.88 | GRIN2B (0.61) | GRIN2BGRIN1 | |
| SCHEMBL28677627 | 0.81 | GRIN2B (0.52) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22787239 | 0.78 | GRIN2B (0.52) | GRIN2BGRIN1KCNH2 | |
| SCHEMBL22772490 | 0.78 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| SCHEMBL29526718 | 0.78 | GRIN1 (1.00) | GRIN2BGRIN1 | |
| Hydrochloric Acid SCHEMBL22770941 | 0.77 | GRIN2B (0.51) | GRIN2BGRIN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983072-A1 | PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-04-20 | — | — | EP | disclosed |