Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 1.00 |
| ▸ | RELA | Q04206 | 6/20 | 0.71 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.56 |
| ▸ | TUBB | P07437 | 2/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739987 | 1.00 | APP (1.00) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL2952824 | 1.00 | APP (1.00) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL22050352 | 0.87 | APP (0.77) | APPRELANFE2L2TUBB4ATUBB | |
| SCHEMBL10338773 | 0.87 | RELA (0.85) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL699632 | 0.83 | RELA (1.00) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL13778224 | 0.83 | RELA (1.00) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL699631 | 0.83 | RELA (1.00) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL9789514 | 0.81 | APP (0.67) | APPRELANFE2L2TRPA1ESR1 | |
| SCHEMBL698667 | 0.81 | APP (0.74) | APPRELANFE2L2CYP19A1 | |
| SCHEMBL9789520 | 0.81 | APP (0.67) | APPRELANFE2L2TRPA1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-110072842-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-1432453-B1 | STILBENE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | UNIV PENNSYLVANIA (US) | 2013-08-14 | — | — | EP | disclosed |
| US-7759502-B2 | Useful for inhibiting the aggregation of amyloid protein to form amyloid deposit | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-07-20 | — | — | US | disclosed |
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2008-05-08 | — | — | US | disclosed |
| US-7297820-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-11-20 | — | — | US | disclosed |
| US-7250525-B2 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2007-07-31 | — | — | US | disclosed |
| CN-1299777-C | Stilbene derivatives and their use for binding and imaging amyloid plaques | UNIV PENNSYLVANIA (US) | 2007-02-14 | — | — | CN | disclosed |
| US-20060002853-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2006-01-05 | — | — | US | disclosed |
| CN-1549731-A | Stilbene derivatives and their use for binding and imaging amyloid plaques | ��Ϧ�������ݴ�ѧ���»� | 2004-11-24 | — | — | CN | disclosed |
| US-20030149250-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060002853-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | APP, APBA1, PSEN1 | APP 1/4885RELA 2968/4885NFE2L2 2543/4885 |
| US-20080108840-A1 | Stilbene Derivatives And Their Use For Binding And Imaging Amyloid Plaques | APP, APBA1, PSEN1 | APP 1/4885RELA 2968/4885NFE2L2 2543/4885 |
| US-20030149250-A1 | Stilbene derivatives and their use for binding and imaging amyloid plaques | APP, APBA1, PSEN1 | APP 1/4885RELA 2968/4885NFE2L2 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.