⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4287590 | 1.00 | — | — | |
| SCHEMBL761864 | 1.00 | — | — | |
| SCHEMBL2890441 | 0.97 | GABRR1 (0.52) | — | |
| Hydrochloric Acid SCHEMBL364236 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL16763788 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL25299022 | 0.97 | — | — | |
| SCHEMBL4883600 | 0.97 | GABRR1 (0.52) | — | |
| SCHEMBL14296901 | 0.86 | GABRR1 (0.48) | — | |
| SCHEMBL9470477 | 0.85 | GABRR1 (0.42) | — | |
| SCHEMBL11938161 | 0.84 | GABRR1 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072656-B | Preparation method (implementation method) of composition for boron neutron capture therapy of malignant tumor | 马丁内斯国际研发中心 | 2023-03-10 | — | — | CN | claimed |
| CN-111303153-B | High-brightness wash-free SNAP-tag probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2022-07-15 | — | — | CN | claimed |
| CN-114072656-A | Preparation method (implementation method) of composition for boron neutron capture therapy of malignant tumor | 马丁内斯国际研发中心 | 2022-02-18 | — | — | CN | claimed |
| WO-2020246913-A1 | METHOD OF PRODUCING A COMPOSITION FOR BORON NEUTRON CAPTURE THERAPY OF MALIGNANT TUMORS (EMBODIMENTS) | АВТОНОМНОЕ НЕКОММЕРЧЕСКОЕ ОБЪЕДИНЕНИЕ "МЕЖДУНАРОДНЫЙ НАУЧНО- ИССЛЕДОВАТЕЛЬСКИЙ ЦЕНТР ИННОВАЦИОННЫХ ТЕХНОЛОГИЙ "МАРТИНЕКС" (АНО "МНИЦИТ МАРТИНЕКС") | 2020-12-10 | — | — | WO | claimed |
| CN-111659436-A | Electronegative heteroatom-transition metal co-doped carbon-based non-noble metal electrocatalyst and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2020-09-15 | — | — | CN | claimed |
| CN-111303153-A | High-brightness wash-free SNAP-tag probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2020-06-19 | — | — | CN | claimed |
| US-8809326-B2 | Isoquinolinone Rho kinase inhibitors | AERIE PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-7662904-B2 | polyethersulfone copolymers; thermal stability, chemical resistance and mechanical strength due to their structural and crosslinked characteristics; uniform thickness when they are used for optical films, sheets, and display; electrooptic devices | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-02-16 | — | — | US | claimed |
| EP-2068878-A2 | RHO KINASE INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2009-06-17 | — | — | EP | claimed |
| US-20080161297-A1 | e.g. N-(7-Chloro-1-oxo-1,2-dihydro-isoquinolin-6-yl)-2-dimethylamino-2-phenyl-acetamide; hypertension, atherosclerosis, restenosis, stroke, heart failure, coronary vasospasm, cerebral vasospasm, ischemia/reperfusion injury, pulmonary hypertension, angina, myocardial infarction, | ALCON INC. (CH) | 2008-07-03 | — | — | US | claimed |
| WO-2008036540-A2 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-27 | — | — | WO | claimed |
| US-20060217518-A1 | Aromatic polyether resins crosslinked by amic acid or imide side chain | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2006-09-28 | — | — | US | claimed |
| US-20260001914-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | MERCK SHARP & DOHME LLC (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250388606-A1 | AZAQUINAZOLINE PAN-KRAS INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
| US-20250320197-A1 | THYROID HORMONE RECEPTOR AGONISTS AND USE THEREOF | ECCOGENE INC (US) | 2025-10-16 | — | — | US | disclosed |
| US-12398154-B2 | Azaquinazoline pan-KRas inhibitors | Mirati Therapeutics, Inc. (US) | 2025-08-26 | — | — | US | disclosed |
| US-20060217518-A1 | Aromatic polyether resins crosslinked by amic acid or imide side chain | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2006-09-28 | — | — | US | disclosed |
| EP-1671649-A1 | REMEDY FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
| US-20060039974-A1 | Sustained release preparation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-02-23 | — | — | US | disclosed |
| EP-1537880-A1 | SUSTAINED RELEASE PREPARATION | Takeda Pharmaceutical Company Limited (JP) | 2005-06-08 | — | — | EP | disclosed |