SCHEMBL4883600

SCHEMBL4883600

NC1CC(C(=O)O)CC(C(=O)O)C1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.52
ABAT P80404 2/20 0.43
SLC6A12 P48065 3/20 0.40
SLC6A11 P48066 3/20 0.40
SLC6A13 Q9NSD5 3/20 0.40
CYP2C19 P33261 3/20 0.39
CYP1A2 P05177 3/20 0.39
ALOX15 P16050 3/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP2D6 P10635 3/20 0.37
LMNA P02545 2/20 0.37
PLG P00747 1/20 0.37
PLAT P00750 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
SLC6A4 P31645 1/20 0.37
ACE P12821 1/20 0.37
OAT P04181 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL295283 0.97
SCHEMBL4287590 0.97
SCHEMBL761864 0.97
Hydrochloric Acid SCHEMBL25299022 0.94
SCHEMBL2890441 0.94 GABRR1 (0.52) GABRR1ABATSLC6A12SLC6A11SLC6A13
Hydrochloric Acid SCHEMBL16763788 0.94
Hydrochloric Acid SCHEMBL364236 0.94
SCHEMBL8204743 0.84 CYP2C19 (0.50) GABRR1ABATSLC6A11CYP2C19CYP1A2
SCHEMBL6542917 0.84 CYP2C19 (0.50) GABRR1ABATSLC6A11CYP2C19CYP1A2
SCHEMBL375124 0.84 CYP2C19 (0.50) GABRR1ABATSLC6A11CYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169759-B1 Tetrapeptide inhibitors of β-secretase ELAN PHARMACEUTICALS, INC. (US) 2007-01-30 US claimed
US-20050182138-A1 Dipeptide inhibitors of beta-secretase ELAN PHARMACEUTICALS, INC. 2005-08-18 US claimed
US-6864240-B1 Dipeptide inhibitors of β-secretase ELAN PHARMACEUTICALS, INC. (US) 2005-03-08 US claimed
EP-1192177-A1 STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE Elan Pharmaceuticals, Inc. (US) 2002-04-03 EP claimed
WO-2000077030-A1 STATINE-DERIVED TETRAPEPTIDE INHIBITORS OF BETA-SECRETASE ELAN PHARMACEUTICALS, INC. (US) 2000-12-21 WO claimed
EP-4692949-A1 POSITIVELY CHARGEABLE TONER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT, TONER SET, AND IMAGE FORMING METHOD Zeon Corporation (JP) 2026-02-11 EP disclosed
WO-2024202238-A1 POSITIVELY CHARGEABLE TONER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT, TONER SET, AND IMAGE FORMING METHOD 日本ゼオン株式会社 2024-10-03 WO disclosed
US-11753500-B2 Epoxy resin solution UNITIKA LTD. (JP) 2023-09-12 US disclosed
CN-113396173-B Epoxy resin solution 尤尼吉可株式会社 2023-09-12 CN disclosed
US-20220106435-A1 EPOXY RESIN SOLUTION UNITIKA LTD. (JP) 2022-04-07 US disclosed
EP-3919541-A1 EPOXY RESIN SOLUTION Unitika Ltd. (JP) 2021-12-08 EP disclosed
CN-113396173-A Epoxy resin solution 尤尼吉可株式会社 2021-09-14 CN disclosed
US-6992081-B2 Compounds to treat Alzheimer's disease ELAN PHARMACEUTICALS, INC. (US) 2006-01-31 US disclosed
US-20040214846-A1 Compounds to treat Alzheimer's disease ELAN PHARMACEUTICALS, INC. 2004-10-28 US disclosed
US-6737420-B2 A SUBSTITUTED HYDROXYETHYLENE COMPOUND USEFUL FOR TREATING ALZHEIMER'S DISEASE, MILD COGNITIVE IMPAIRMENT, DOWN'S SYNDROME, HEREDIATARY CEREBRAL HEMMORRHAGE WITH AMYLOIDOSIS, DEGENERATIVE DEMENTIA ELAN PHARMACEUTICALS, INC. 2004-05-18 US disclosed
US-20030013881-A1 Compounds to treat Alzheimer's disease ELAN PHARMACEUTICALS, INC. 2003-01-16 US disclosed
EP-1265849-A2 COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE Elan Pharmaceuticals, Inc. (US) 2002-12-18 EP disclosed
US-20020022623-A1 Compounds to treat alzheimer's disease ELAN PHARMACEUTICALS, INC. 2002-02-21 US disclosed
US-20020019403-A1 Methods to treat alzheimer's disease ELAN PHARMACEUTICALS, INC. 2002-02-14 US disclosed
WO-2001070672-A2 COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE ELAN PHARMACEUTICALS, INC. (US) 2001-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040214846-A1 Compounds to treat Alzheimer's disease PSEN1, PSEN2, BACE1 GABRR1 1469/4885ABAT 1110/4885SLC6A12 3870/4885
US-20020019403-A1 Methods to treat alzheimer's disease PSEN1, PSEN2, BACE1 GABRR1 804/4885ABAT 1009/4885SLC6A12 3025/4885
US-20030013881-A1 Compounds to treat Alzheimer's disease PSEN2, PSEN1, BACE1 GABRR1 1308/4885ABAT 753/4885SLC6A12 3259/4885
US-20020022623-A1 Compounds to treat alzheimer's disease PSEN1, PSEN2, BACE1 GABRR1 1469/4885ABAT 1110/4885SLC6A12 3870/4885
US-20050182138-A1 Dipeptide inhibitors of beta-secretase BACE1, APP, BACE2 GABRR1 1441/4885ABAT 476/4885SLC6A12 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.