Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29528398 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL253014 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL252804 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL254128 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL29527970 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL253015 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL254127 | 1.00 | LMNA (0.48) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL253983 | 0.83 | LMNA (0.43) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL253969 | 0.83 | LMNA (0.43) | LMNATP53HTTADRA2CSMN1; SMN2 | |
| SCHEMBL29528426 | 0.83 | LMNA (0.43) | LMNATP53HTTADRA2CSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111419830-B | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes | 比皮艾思药物研发有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | disclosed |
| CN-109939092-B | Phenyl carbamate compounds for use in preventing or treating pediatric epilepsy and epilepsy-related syndrome | 比皮艾思药物研发有限公司 | 2022-03-22 | — | — | CN | disclosed |