Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.71 |
| ▸ | CA1 | P00915 | 6/20 | 0.71 |
| ▸ | CA2 | P00918 | 6/20 | 0.71 |
| ▸ | CA7 | P43166 | 6/20 | 0.71 |
| ▸ | CA9 | Q16790 | 6/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.71 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.71 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2952989 | 0.93 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4472418 | 0.86 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL14812864 | 0.85 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL158999 | 0.85 | CA12 (0.74) | CA12CA1CA2CA7CA9 | |
| Methyl 2,4-Dihydroxybenzoate SCHEMBL382883 | 0.83 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Methyl 2,4-Dihydroxybenzoate SCHEMBL30917273 | 0.83 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7563000 | 0.83 | SLC6A3 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL131661 | 0.82 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| Methyl 2,4-Dihydroxybenzoate SCHEMBL28334880 | 0.82 | CA12 (0.96) | CA12CA1CA2CA7CA9 | |
| SCHEMBL20244996 | 0.82 | CA12 (0.69) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | claimed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | claimed |
| CN-101346359-A | 5, 5' position connecting 1, 1'-biphenyl shaft chiral ligand and its synthesizing method | UNIV SHANGHAI JIAOTONG (CN) | 2009-01-14 | — | — | CN | claimed |
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | disclosed |
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | disclosed |
| US-7754891-B2 | chiral ligand may coordinate with metal ions, such as copper, palladium and the like, to catalyze such reactions as asymmetric cyclopropylation reaction, intramolecular Wacker-Type cyclization reaction, asymmetric oxidation reaction of olefin, and intramolecular [2+1] ring addition reaction | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2010-07-13 | — | — | US | disclosed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | disclosed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | disclosed |
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | SHANGHAI JIAOTONG UNIVERSITY (CN) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156829-A1 | 5,5'- POSITION LINKED 1,1'- BIPHENYL AXIAL CHIRAL LIGAND AND METHOD FOR PREPARING THE SAME | AHR, CXCR5, CYP1B1 | CA12 4035/4885CA1 2506/4885CA2 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.