Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 18/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766219 | 1.00 | TTK (0.61) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL2950470 | 0.91 | TTK (0.59) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL2950466 | 0.91 | TTK (0.59) | TTKPIK3CBMAPK8PTK2 | |
| SCHEMBL2956334 | 0.88 | TTK (0.77) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL3705855 | 0.86 | TTK (0.66) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL4764715 | 0.86 | TTK (0.78) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL29446172 | 0.86 | TTK (0.77) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL2946927 | 0.86 | TTK (0.77) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL3702624 | 0.85 | TTK (0.66) | TTKADORA3PIK3CBMAPK8PTK2 | |
| SCHEMBL4764770 | 0.84 | TTK (0.63) | TTKADORA3PIK3CBMAPK8PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |