Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL231219 | 0.89 | HSD17B10 (0.55) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL3188564 | 0.89 | HSD17B10 (0.55) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL889059 | 0.89 | HSD17B10 (0.55) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL190173 | 0.88 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL40804 | 0.88 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL338312 | 0.88 | HSD17B10 (0.49) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL10082580 | 0.85 | HPGD (0.50) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL525478 | 0.85 | HPGD (0.50) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL15317053 | 0.85 | HPGD (0.50) | HSD17B10SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL1991177 | 0.83 | HSD17B10 (0.45) | HSD17B10SMN1; SMN2ALDH1A1HPGDCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217070-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Scorpion Therapeutics, Inc. (US) | 2023-08-02 | — | — | EP | disclosed |
| WO-2022066734-A1 | PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |