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Vasopressin

Vasopressin

SCHEMBL29530914

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nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AVPR1AAVPR1BAVPR2

The experimentally established mechanism targets of Vasopressin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A known ✓ P37288 7/20 0.97
▸ AVPR1B known ✓ P47901 5/20 0.97
▸ AVPR2 known ✓ P30518 4/20 0.97
▸ OXTR P30559 4/20 0.97
▸ PTGS1 P23219 1/20 0.86
▸ TBXA2R P21731 1/20 0.70
▸ PDE4D Q08499 1/20 0.70
▸ PDE3A Q14432 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vasopressin SCHEMBL17874853 0.98 AVPR1A (1.00) AVPR1AAVPR1BAVPR2OXTRPTGS1
Vasopressin SCHEMBL29688276 0.98 AVPR1A (1.00) AVPR1AAVPR1BAVPR2OXTRPTGS1
Vasopressin SCHEMBL18937546 0.98 AVPR1A (1.00) AVPR1AAVPR1BAVPR2OXTRPTGS1
Vasopressin SCHEMBL19712236 0.98 AVPR1A (1.00) AVPR1AAVPR1BAVPR2OXTRPTGS1
SCHEMBL23879427 0.96 AVPR1A (0.96) AVPR1AAVPR1BAVPR2OXTRPTGS1
SCHEMBL18476287 0.96 AVPR1A (0.96) AVPR1AAVPR1BAVPR2OXTRPTGS1
SCHEMBL19733909 0.96 AVPR1A (0.96) AVPR1AAVPR1BAVPR2OXTRPTGS1
SCHEMBL24390785 0.96 AVPR1A (0.96) AVPR1AAVPR1BAVPR2OXTRPTGS1
Vasopressin SCHEMBL1172390 0.96 AVPR1A (0.95) AVPR1AAVPR1BAVPR2OXTRPTGS1
SCHEMBL29500557 0.96 AVPR1A (0.95) AVPR1AAVPR1BAVPR2OXTRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743176-A1 DEUTERATED 1,3 DIHYDRO -2H-INDOLE-2-ONE DERIVATIVES HMNC Holding GmbH (DE) 2026-05-20 — — EP disclosed
US-20250034117-A1 Deuterated 1,3 Dihydro -2H-indole-2-one derivatives HMNC Holding GmbH (DE) 2025-01-30 — — US disclosed
WO-2025012460-A1 DEUTERATED 1,3 DIHYDRO -2H-INDOLE-2-ONE DERIVATIVES HMNC Holding GmbH (DE) 2025-01-16 — — WO disclosed
US-20230356185-A1 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2023-11-09 — — US disclosed
EP-4217106-A1 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES University Of South Australia (AU) 2023-08-02 — — EP disclosed
WO-2022061418-A9 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2022-04-28 — — WO disclosed
WO-2022061418-A1 IMPROVEMENTS IN LIQUID CHROMATOGRAPHY SUBSTRATES UNIVERSITY OF SOUTH AUSTRALIA (AU) 2022-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034117-A1 Deuterated 1,3 Dihydro -2H-indole-2-one derivatives IDO1, IDO2, TPH1 AVPR1A 204/4885AVPR1B 187/4885AVPR2 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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