Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.45 |
| ▸ | CALCR | P30988 | 4/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29530685 | 0.96 | CALCR (0.45) | C5AR1CALCRACECRHR1CRHR2 | |
| SCHEMBL29530818 | 0.94 | CRHR1 (0.46) | C5AR1CALCRACECRHR1CRHR2 | |
| SCHEMBL31573968 | 0.90 | C5AR1 (0.50) | C5AR1CALCRCRHR1CRHR2HCRTR1 | |
| SCHEMBL31721983 | 0.90 | CALCR (0.50) | C5AR1CALCRACECRHR1CRHR2 | |
| SCHEMBL29530459 | 0.89 | CRHR1 (0.48) | C5AR1CALCRCRHR1CRHR2MC4R | |
| SCHEMBL31573972 | 0.88 | C5AR1 (0.48) | C5AR1CALCRCRHR1CRHR2ITGB3 | |
| SCHEMBL29530736 | 0.87 | C5AR1 (0.50) | C5AR1CALCRCRHR1CRHR2ITGB3 | |
| SCHEMBL29530561 | 0.86 | SLC15A2 (0.39) | C5AR1CALCRCRHR1CRHR2 | |
| SCHEMBL31688321 | 0.86 | CALCR (0.51) | C5AR1CALCRCRHR1CRHR2MC4R | |
| SCHEMBL31683252 | 0.86 | CALCR (0.51) | C5AR1CALCRCRHR1CRHR2MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4039710-B1 | ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123 | SANOFI SA (FR) | 2026-03-25 | — | — | EP | disclosed |
| EP-4039710-A2 | ANTI-CD3 ANTIBODIES, ANTI-CD123 ANTIBODIES AND BISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO CD3 AND/OR CD123 | SANOFI (FR) | 2022-08-10 | — | — | EP | disclosed |
| CN-114230668-A | anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 | 赛诺菲 | 2022-03-25 | — | — | CN | disclosed |
| CN-114230667-A | anti-CD 3 antibodies, anti-CD 123 antibodies, and bispecific antibodies that specifically bind to CD3 and/or CD123 | 赛诺菲 | 2022-03-25 | — | — | CN | disclosed |