Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048660 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| SCHEMBL5864571 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| SCHEMBL26091219 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| SCHEMBL8140360 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| SCHEMBL9756598 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| SCHEMBL26091221 | 0.93 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| Hydrochloric Acid SCHEMBL5013954 | 0.92 | KCNJ1 (0.46) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| Hydrochloric Acid SCHEMBL5013957 | 0.92 | KCNJ1 (0.46) | KCNJ1KCNH2TBXA2RHRH3ADRB1 | |
| Acetic Acid SCHEMBL21489543 | 0.86 | TBXA2R (0.42) | KCNJ1KCNH2TBXA2RHRH3KMT2A | |
| SCHEMBL9339492 | 0.85 | KCNJ1 (0.47) | KCNJ1KCNH2TBXA2RHRH3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754765-B2 | Copper chelators for treating ocular inflammation | Radical Vision Therapeutics Inc (CA) | 2010-07-13 | — | — | US | disclosed |
| US-20030232799-A1 | Copper chelators for treating ocular Inflammation | LI, NING, DR. (CN) | 2003-12-18 | — | — | US | disclosed |
| EP-1370254-A2 | COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION | The University of British Columbia (CA) | 2003-12-17 | — | — | EP | disclosed |
| US-20030055113-A1 | Copper chelators for treating ocular inflammation | UNIVERSITY OF BRITISH COLUMBIA, THE (CA) | 2003-03-20 | — | — | US | disclosed |
| WO-2002043722-A2 | COPPER CHELATORS FOR TREATING OCULAR INFLAMMATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2002-06-06 | — | — | WO | disclosed |