SCHEMBL5864571

SCHEMBL5864571

O=[N+]([O-])c1ccc(CC2CNCCNCCNCCNCCNCCN2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 2/20 0.47
KCNH2 Q12809 2/20 0.47
TBXA2R P21731 1/20 0.44
HRH3 Q9Y5N1 1/20 0.43
ADRB1 P08588 1/20 0.42
SIRT6 Q8N6T7 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.41
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
AR P10275 1/20 0.39
IDO1 P14902 1/20 0.38
LTA4H P09960 1/20 0.38
ADRA2A P08913 1/20 0.38
PNMT P11086 1/20 0.38
GFER P55789 1/20 0.37
PARP1 P09874 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3048660 1.00 KCNJ1 (0.47) KCNJ1KCNH2TBXA2RHRH3ADRB1
SCHEMBL8140360 1.00 KCNJ1 (0.47) KCNJ1KCNH2TBXA2RHRH3ADRB1
SCHEMBL9756598 1.00 KCNJ1 (0.47) KCNJ1KCNH2TBXA2RHRH3ADRB1
SCHEMBL26091219 1.00 KCNJ1 (0.47) KCNJ1KCNH2TBXA2RHRH3ADRB1
SCHEMBL26091221 1.00 KCNJ1 (0.47) KCNJ1KCNH2TBXA2RHRH3ADRB1
Hydrochloric Acid SCHEMBL5013957 0.99 KCNJ1 (0.46) KCNJ1KCNH2TBXA2RHRH3ADRB1
Hydrochloric Acid SCHEMBL5013954 0.99 KCNJ1 (0.46) KCNJ1KCNH2TBXA2RHRH3ADRB1
SCHEMBL2953111 0.93 KCNJ1 (0.44) KCNJ1KCNH2TBXA2RHRH3ADRB1
Acetic Acid SCHEMBL21489543 0.92 TBXA2R (0.42) KCNJ1KCNH2TBXA2RHRH3KMT2A
Hydrochloric Acid SCHEMBL6013527 0.90 KCNJ1 (0.41) KCNJ1KCNH2TBXA2RHRH3ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7132513-B2 Bifunctional chelating agent EUROPEAN COMMUNITY (BE) 2006-11-07 US disclosed
US-20030027302-A1 Bifunctional chelating agent INSERM INSTITUT NATIOANL DE LA SANTE ET DE LA REOHERCHE MEDICALE (FR) 2003-02-06 US disclosed
EP-1263741-A1 BIFUNCTIONAL CHELATING AGENT EUROPEAN COMMUNITY (BE) 2002-12-11 EP disclosed
WO-2001068618-A1 BIFUNCTIONAL CHELATING AGENT EUROPEAN COMMUNITY (BE) 2001-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030027302-A1 Bifunctional chelating agent H1-2, H1-0, H1-5 KCNJ1 1403/4885KCNH2 77/4885TBXA2R 3835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.