Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 10/20 | 0.71 |
| ▸ | IL1RN | P18510 | 9/20 | 0.60 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.60 |
| ▸ | ECE1 | P42892 | 5/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839328 | 0.93 | ERAP2 (0.73) | ERAP2IL1RNERAP1ECE1MMP1 | |
| SCHEMBL31575706 | 0.93 | ERAP2 (0.62) | ERAP2IL1RNERAP1ECE1ACE | |
| SCHEMBL31134794 | 0.92 | ERAP2 (0.77) | ERAP2IL1RNERAP1ECE1MMP1 | |
| SCHEMBL29815684 | 0.91 | ERAP2 (0.76) | ERAP2IL1RNERAP1ECE1MMP1 | |
| SCHEMBL30123123 | 0.91 | ERAP2 (0.76) | ERAP2IL1RNERAP1ECE1MMP1 | |
| SCHEMBL31388803 | 0.90 | ERAP2 (0.72) | ERAP2IL1RNERAP1ECE1MMP1 | |
| SCHEMBL9842926 | 0.90 | ERAP2 (0.68) | ERAP2IL1RNERAP1ECE1 | |
| SCHEMBL29470162 | 0.90 | ERAP2 (0.71) | ERAP2IL1RNERAP1ECE1ACE | |
| SCHEMBL29470163 | 0.90 | ERAP2 (0.71) | ERAP2IL1RNERAP1ECE1ACE | |
| SCHEMBL31720529 | 0.90 | ERAP2 (0.74) | ERAP2IL1RNERAP1ECE1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |