Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | NPY4R | P50391 | 13/20 | 0.49 |
| ▸ | NPY1R | P25929 | 8/20 | 0.49 |
| ▸ | NPY2R | P49146 | 6/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29876897 | 0.93 | NPY4R (0.51) | KDM1ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29666825 | 0.92 | CTSC (0.48) | KDM1AGHSRNPY4RNPY1RNPY2R | |
| SCHEMBL29932164 | 0.91 | NPY4R (0.51) | KDM1ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7174455 | 0.90 | CTSC (0.49) | GHSRNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7174450 | 0.90 | CTSC (0.49) | GHSRNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29387797 | 0.90 | CTSC (0.49) | GHSRNPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30540727 | 0.90 | NPY4R (0.47) | KDM1ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7643925 | 0.89 | KDM1A (0.49) | KDM1ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL29895402 | 0.89 | NPY4R (0.47) | KDM1ANPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL7643912 | 0.89 | KDM1A (0.49) | KDM1ANPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |