Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.60 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | ECE1 | P42892 | 7/20 | 0.53 |
| ▸ | IL1RN | P18510 | 3/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31720961 | 1.00 | ERAP2 (0.60) | ERAP2MAGI3KDM4EMAPTMEN1 | |
| SCHEMBL29352054 | 0.94 | MAGI3 (0.64) | ERAP2MAGI3KDM4EMAPTMEN1 | |
| SCHEMBL30123199 | 0.93 | ERAP2 (0.63) | ERAP2MAGI3KDM4EMAPTMEN1 | |
| SCHEMBL29828545 | 0.92 | KDM4E (0.57) | ERAP2KDM4EMAPTMEN1LMNA | |
| SCHEMBL29559633 | 0.91 | ACE (0.62) | ERAP2MAGI3KDM4EMAPTMEN1 | |
| SCHEMBL31171635 | 0.91 | CASP1 (0.55) | ERAP2MAGI3KDM4EMAPTMEN1 | |
| SCHEMBL29638036 | 0.90 | KDM4E (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL29362572 | 0.90 | KDM4E (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL21641804 | 0.90 | KDM4E (0.67) | KDM4EMAPTMEN1LMNAMPO | |
| SCHEMBL9822472 | 0.90 | KDM4E (0.67) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |