Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 18/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.41 |
| ▸ | CTSD | P07339 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30254038 | 0.91 | BACE1 (0.38) | BACE1CTSD | |
| SCHEMBL30567410 | 0.91 | BACE1 (0.38) | BACE1CTSD | |
| SCHEMBL30312061 | 0.90 | BACE1 (0.46) | BACE1BACE2CTSD | |
| SCHEMBL30799789 | 0.90 | BACE1 (0.51) | BACE1BACE2CTSD | |
| SCHEMBL30274692 | 0.89 | NAALAD2 (0.39) | BACE1 | |
| SCHEMBL8437180 | 0.89 | MME (0.37) | BACE1 | |
| SCHEMBL8437182 | 0.89 | MME (0.37) | BACE1 | |
| SCHEMBL31239692 | 0.89 | BACE1 (0.39) | BACE1BACE2CTSD | |
| SCHEMBL31721057 | 0.89 | OPRM1 (0.36) | BACE1 | |
| SCHEMBL30476106 | 0.88 | BACE1 (0.49) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |