SCHEMBL29531597

SCHEMBL29531597

NCCCC[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)CN)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 7/20 0.49
▸ NMT2 O60551 6/20 0.49
▸ SLC15A2 Q16348 1/20 0.48
▸ FOLH1 Q04609 1/20 0.47
▸ SLC6A5 Q9Y345 1/20 0.46
▸ CPB2 Q96IY4 4/20 0.41
▸ TLR2 O60603 1/20 0.41
▸ SIRT6 Q8N6T7 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531769 0.97 NMT1 (0.53) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL31757269 0.92 NMT1 (0.51) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL32672545 0.91 NMT1 (0.51) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL30455335 0.90 NMT1 (0.50) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL30932293 0.89 FOLH1 (0.49) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL30397555 0.89 NMT1 (0.53) NMT1NMT2SLC15A2SLC6A5TLR2
SCHEMBL30398397 0.89 NMT1 (0.53) NMT1NMT2SLC15A2SLC6A5TLR2
SCHEMBL29606164 0.89 NMT1 (0.56) NMT1NMT2SLC15A2SLC6A5CPB2
SCHEMBL29532146 0.89 SLC15A2 (0.58) NMT1NMT2SLC15A2FOLH1SLC6A5
SCHEMBL31213154 0.88 SLC6A5 (0.45) NMT1NMT2SLC15A2SLC6A5TLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 — — US disclosed
CN-110669146-B Active peptide capable of specifically blocking binding site of adapter protein Nck for preventing intestinal EPEC infection 常州大学 2023-05-23 — — CN disclosed
US-20220273830-A1 COMPOUNDS AND METHODS OF USE Edinburgh Molecular Imaging Limited (GB) 2022-09-01 — — US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 — — US disclosed
EP-3983019-A1 COMPOUNDS AND METHODS OF USE Edinburgh Molecular Imaging Limited (GB) 2022-04-20 — — EP disclosed
EP-3773750-B1 FORMULATION AND METHOD OF PREPARATION GE HEALTHCARE AS (NO) 2022-04-20 — — EP disclosed
CN-114222592-A Compounds and methods of use 爱丁堡分子成像有限公司 2022-03-22 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220273830-A1 COMPOUNDS AND METHODS OF USE VIP, QPCT, CALCRL NMT1 179/4885NMT2 145/4885SLC15A2 2813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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