Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | RAMP3 | O60896 | 5/20 | 0.35 |
| ▸ | CALCR | P30988 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686002 | 0.91 | MAPK8 (0.42) | KEAP1CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL29590531 | 0.90 | MAPK8 (0.48) | KEAP1CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL29924267 | 0.90 | PRCP (0.41) | KEAP1PRCPDPP7MEN1KMT2A | |
| SCHEMBL29548137 | 0.90 | PRCP (0.41) | KEAP1PRCPDPP7MEN1KMT2A | |
| SCHEMBL30686003 | 0.87 | MAPK8 (0.48) | KEAP1CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL30686004 | 0.87 | MAPK8 (0.48) | KEAP1CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL29980620 | 0.86 | PRCP (0.39) | KEAP1CALCRLMAPK8MAPK9MAPK10 | |
| SCHEMBL30974174 | 0.86 | KDM1A (0.38) | KEAP1MAPK8MAPK9MAPK10PRCP | |
| SCHEMBL30686009 | 0.86 | MAPK8 (0.49) | KEAP1MAPK8MAPK9MAPK10PRCP | |
| SCHEMBL31720924 | 0.86 | PRCP (0.41) | KEAP1CALCRLMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |