SCHEMBL30686002

SCHEMBL30686002

C[C@@H](O)[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK8 P45983 1/20 0.42
▸ MAPK9 P45984 1/20 0.42
▸ MAPK10 P53779 1/20 0.42
▸ KEAP1 Q14145 1/20 0.41
▸ PRCP P42785 2/20 0.40
▸ DPP7 Q9UHL4 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CALCRL Q16602 1/20 0.37
▸ KDM1A O60341 2/20 0.36
▸ CDYL2 Q8N8U2 1/20 0.35
▸ CDYL Q9Y232 1/20 0.35
▸ REN P00797 1/20 0.35
▸ CTSC P53634 1/20 0.35
▸ GHSR Q92847 1/20 0.35
▸ FURIN P09958 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29680012 0.94 MAPK8 (0.48) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL31720924 0.93 PRCP (0.41) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL29531541 0.93 PRCP (0.41) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL30686009 0.93 MAPK8 (0.49) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL30686003 0.92 MAPK8 (0.48) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL30686004 0.92 MAPK8 (0.48) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL29531747 0.91 KEAP1 (0.45) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL29531712 0.89 PRCP (0.42) MAPK8MAPK9MAPK10KEAP1PRCP
SCHEMBL30974540 0.89 NPY4R (0.51) MAPK8MAPK9MAPK10KEAP1KDM1A
SCHEMBL31019315 0.88 PRCP (0.41) MAPK8MAPK9MAPK10KEAP1PRCP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547686-A1 COMPOUND-DIAGNOSTIC MARKER FOR UTERINE BODY CANCER, METHOD FOR DETECTING ENZYMATIC ACTIVITY, METHOD FOR DIAGNOSIS OF UTERINE BODY CANCER, KIT COMPRISING THE COMPOUND, USES OF THE COMPOUND AND METHOD FOR THE TREATMENT OF UTERINE BODY CANCER Urteste S.A. (PL) 2025-05-07 — — EP claimed
WO-2024005658-A1 COMPOUND-DIAGNOSTIC MARKER FOR UTERINE BODY CANCER, METHOD FOR DETECTING ENZYMATIC ACTIVITY, METHOD FOR DIAGNOSIS OF UTERINE BODY CANCER, KIT COMPRISING THE COMPOUND, USES OF THE COMPOUND AND METHOD FOR THE TREATMENT OF UTERINE BODY CANCER URTESTE S.A. (PL) 2024-01-04 — — WO claimed
US-20250376711-A1 COMPOUND-DIAGNOSTIC MARKER FOR UTERINE BODY CANCER, METHOD FOR DETECTING ENZYMATIC ACTIVITY, METHOD FOR DIAGNOSIS OF UTERINE BODY CANCER, KIT COMPRISING THE COMPOUND, USES OF THE COMPOUND AND METHOD FOR THE TREATMENT OF UTERINE BODY CANCER URTESTE S.A. (PL) 2025-12-11 — — US disclosed
EP-4547686-A1 COMPOUND-DIAGNOSTIC MARKER FOR UTERINE BODY CANCER, METHOD FOR DETECTING ENZYMATIC ACTIVITY, METHOD FOR DIAGNOSIS OF UTERINE BODY CANCER, KIT COMPRISING THE COMPOUND, USES OF THE COMPOUND AND METHOD FOR THE TREATMENT OF UTERINE BODY CANCER Urteste S.A. (PL) 2025-05-07 — — EP disclosed
CN-119451973-A Compound-diagnostic marker for endometrial cancer, method for detecting enzymatic activity, method for diagnosing endometrial cancer, kit containing same, use of same and method for treating endometrial cancer 尔特斯特公司 2025-02-14 — — CN disclosed
WO-2024005658-A1 COMPOUND-DIAGNOSTIC MARKER FOR UTERINE BODY CANCER, METHOD FOR DETECTING ENZYMATIC ACTIVITY, METHOD FOR DIAGNOSIS OF UTERINE BODY CANCER, KIT COMPRISING THE COMPOUND, USES OF THE COMPOUND AND METHOD FOR THE TREATMENT OF UTERINE BODY CANCER URTESTE S.A. (PL) 2024-01-04 — — WO disclosed
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