Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 2/20 | 0.43 |
| ▸ | CTSC | P53634 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30052733 | 1.00 | DPP7 (0.44) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL29692512 | 0.90 | TERT (0.44) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL30005793 | 0.89 | CALCRL (0.40) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL2870216 | 0.89 | DPP7 (0.44) | DPP7CALCRLPRCPCTSCCYP1A2 | |
| SCHEMBL2870227 | 0.89 | DPP7 (0.44) | DPP7CALCRLPRCPCTSCCYP1A2 | |
| SCHEMBL29396785 | 0.86 | DPP7 (0.46) | DPP7PRCPCTSCCYP1A2CYP3A4 | |
| SCHEMBL29356386 | 0.86 | BACE1 (0.43) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL30353294 | 0.85 | CALCRL (0.49) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL21688326 | 0.83 | DPP7 (0.43) | DPP7CALCRLPRCPCTSCBACE1 | |
| SCHEMBL30051748 | 0.82 | DPP7 (0.44) | DPP7CALCRLPRCPCTSCBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230393140-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2023-12-07 | — | — | US | disclosed |
| EP-4229211-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI International (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2022082006-A1 | BINDING ASSAYS INVOLVING A PLURALITY OF SYNTHETIC COMPOUNDS, TARGETS, AND COUNTER TARGETS | SRI INTERNATIONAL (US) | 2022-04-21 | — | — | WO | disclosed |