Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A1 | P60842 | 18/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | RELA | Q04206 | 1/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18836426 | 1.00 | EIF4A1 (0.68) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| SCHEMBL17414030 | 1.00 | EIF4A1 (0.68) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| SCHEMBL17414004 | 0.94 | EIF4A1 (0.68) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| SCHEMBL18836042 | 0.94 | EIF4A1 (0.70) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| SCHEMBL29531653 | 0.92 | EIF4A1 (0.81) | EIF4A1CYP3A4HIF1APAX8 | |
| SCHEMBL18836582 | 0.92 | EIF4A1 (0.81) | EIF4A1CYP3A4HIF1APAX8 | |
| SCHEMBL17414018 | 0.92 | EIF4A1 (0.81) | EIF4A1CYP3A4HIF1APAX8 | |
| Formic Acid SCHEMBL18836873 | 0.91 | EIF4A1 (0.64) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| Formic Acid SCHEMBL18836876 | 0.91 | EIF4A1 (0.64) | EIF4A1CYP3A4HIF1ANFKB1RELA | |
| Didesmethylrocaglamide SCHEMBL31489959 | 0.90 | EIF4A1 (0.83) | EIF4A1CYP3A4HIF1ANFKB1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998257-A1 | FLAVAGLINE DERIVATIVES | PIERRE FABRE MEDICAMENT (FR) | 2022-05-18 | — | — | EP | disclosed |