Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694210 | 0.84 | TMEM97 (0.60) | TMEM97SIGMAR1KDM4ECARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL8693232 | 0.83 | TMEM97 (0.59) | TMEM97SIGMAR1KDM4ECARM1PRMT6 | |
| SCHEMBL14100151 | 0.83 | TMEM97 (0.72) | TMEM97SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11537473 | 0.81 | SIGMAR1 (0.74) | TMEM97SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27877049 | 0.81 | TMEM97 (0.74) | TMEM97SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8692602 | 0.81 | TMEM97 (0.63) | TMEM97SIGMAR1KDM4ECARM1PRMT6 | |
| SCHEMBL21251621 | 0.80 | TMEM97 (0.72) | TMEM97SIGMAR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8689920 | 0.80 | TMEM97 (0.72) | TMEM97SIGMAR1CYP2D6HRH3DRD2 | |
| SCHEMBL8694338 | 0.80 | TMEM97 (0.69) | TMEM97SIGMAR1KDM4E | |
| Hydrochloric Acid SCHEMBL8691470 | 0.80 | TMEM97 (0.61) | TMEM97SIGMAR1KDM4ECARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3468960-B1 | CHEMICAL COMPOUNDS AS ATF4 PATHWAY INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2022-03-23 | — | — | EP | claimed |