Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.70 |
| ▸ | ECE1 | P42892 | 5/20 | 0.68 |
| ▸ | IL1RN | P18510 | 5/20 | 0.66 |
| ▸ | ACE | P12821 | 2/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.64 |
| ▸ | ANPEP | P15144 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051575 | 1.00 | ERAP2 (0.70) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL29531288 | 1.00 | ERAP2 (0.70) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL30051984 | 0.96 | ERAP2 (0.67) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL30051680 | 0.96 | ECE1 (0.66) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL30051546 | 0.95 | ERAP2 (0.73) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL29531545 | 0.95 | ERAP2 (0.73) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL29531276 | 0.95 | ERAP2 (0.73) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL29556559 | 0.94 | OPRM1 (0.62) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL29555989 | 0.94 | OPRM1 (0.62) | ERAP2ECE1IL1RNACEERAP1 | |
| SCHEMBL30051690 | 0.93 | ERAP2 (0.73) | ERAP2ECE1IL1RNACEERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220040255-A1 | CHEMOTHERAPEUTIC REMODELING OF THE GUT MICROBIOME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-02-10 | — | — | US | claimed |
| US-20220040255-A1 | CHEMOTHERAPEUTIC REMODELING OF THE GUT MICROBIOME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-02-10 | — | — | US | disclosed |