Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.60 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22919301 | 0.85 | KMT2A (0.54) | KMT2ATLR9ATMPSMB5ALDH1A1 | |
| SCHEMBL29533140 | 0.85 | KMT2A (0.54) | KMT2ATLR9ATMPSMB5ALDH1A1 | |
| SCHEMBL807074 | 0.84 | FGFR1 (0.57) | KMT2ATLR9ATMPSMB5ALDH1A1 | |
| Morpholine SCHEMBL28153659 | 0.83 | KMT2A (0.46) | KMT2ATLR9ATMPSMB5AKT1 | |
| Hydrochloric Acid SCHEMBL789680 | 0.83 | FGFR1 (0.55) | KMT2ATLR9ATMPSMB5ALDH1A1 | |
| SCHEMBL22919305 | 0.81 | PSMB5 (0.71) | KMT2ATLR9ATMPSMB5ALDH1A1 | |
| SCHEMBL3359420 | 0.80 | PSMB5 (0.65) | KMT2AATMPSMB5AKT1ALDH1A1 | |
| SCHEMBL29374375 | 0.80 | PSMB5 (0.65) | KMT2AATMPSMB5AKT1ALDH1A1 | |
| SCHEMBL31054483 | 0.78 | PSMB5 (0.63) | KMT2AATMPSMB5AKT1ALDH1A1 | |
| SCHEMBL11792682 | 0.78 | KMT2A (1.00) | KMT2ATLR9ATMAKT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269720-A | acetyl-CoA synthetase short chains2(ACSS2) Small molecule inhibitors of | 库拉德夫制药私人有限公司 | 2022-04-01 | — | — | CN | disclosed |